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Introduction to Numerical Programming A Practical Guide for Scientists and Engineers Using Python and C/C++

Introduction to Numerical Programming A Practical Guide for Scientists and Engineers Using Python and C/C++

Makes Numerical Programming More Accessible to a Wider Audience Bearing in mind the evolution of modern programming most specifically emergent programming languages that reflect modern practice Numerical Programming: A Practical Guide for Scientists and Engineers Using Python and C/C plus plus utilizes the author‘s many years of practical research and teaching experience to offer a systematic approach to relevant programming concepts. Adopting a practical broad appeal this user-friendly book offers guidance to anyone interested in using numerical programming to solve science and engineering problems. Emphasizing methods generally used in physics and engineering from elementary methods to complex algorithms it gradually incorporates algorithmic elements with increasing complexity. Develop a Combination of Theoretical Knowledge Efficient Analysis Skills and Code Design Know-How The book encourages algorithmic thinking which is essential to numerical analysis. Establishing the fundamental numerical methods application numerical behavior and graphical output needed to foster algorithmic reasoning coding dexterity and a scientific programming style it enables readers to successfully navigate relevant algorithms understand coding design and develop efficient programming skills. The book incorporates real code and includes examples and problem sets to assist in hands-on learning. Begins with an overview on approximate numbers and programming in Python and C/C plus plus followed by discussion of basic sorting and indexing methods as well as portable graphic functionality Contains methods for function evaluation solving algebraic and transcendental equations systems of linear algebraic equations ordinary differential equations and eigenvalue problems Addresses approximation of tabulated functions regression integration of one- | Introduction to Numerical Programming A Practical Guide for Scientists and Engineers Using Python and C/C++

GBP 180.00
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Tissue Type Plasminogen Activity Volume I

Tissue Type Plasminogen Activity Volume I

This book is made possible by the enthusiastic contributions of the authors of the chapters. They have been invited from young and active scientists in the field of t-PA research. I am grateful for their contribution and for the fact that all accepted the specifications of their chapter in order to obtain a structured book. Inevitably some overlap does exist; on the one hand to enable controversial or unsettled areas to be discussed by the different experts with a different approach and background. It is a particular pleasure and honor that Dr. T. Astrup as an eye-witness and essential contributor to the history of t-PA discovery and research gives a unique account of the history of t-PA research in the first chapter of the book. | Tissue Type Plasminogen Activity Volume I

GBP 200.00
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Networks of Influence and Power Business Culture and Identity in Liverpool's Merchant Community c.1800 to 1914

Networks of Influence and Power Business Culture and Identity in Liverpool's Merchant Community c.1800 to 1914

During the nineteenth century Liverpool became the heart of an international maritime network. As the 'second city' of Empire its merchants and shipowners operated within a transnational commercial and financial system while its trading connections stimulated the development of new markets and their integration within an increasingly global economy. This ground-breaking volume brings together ten original contributions that reflect upon the development of the city's business community from the early-nineteenth century to the outbreak of the First World War with an emphasis on the period from 1851 to 1912. It offers the first detailed analysis of Liverpool's merchant community within a conceptual and historiographical framework which focuses on the economic social and cultural role of business elites in the nineteenth century. It explores the extent to which business success was predicated on the maintenance of networks of trust; analyses the importance of business culture in structuring commercial operations; and discusses the role of ethics trust and reputation within the changing framework of the business environment. Particular attention is paid to the role of women and the important contribution of the family to commercial success and the maintenance of social networks. Changes in business practice and social networks are also examined within a spatial context in order to assess the impact of the development of a distinct commercial centre and the clustering of commercial activity on interaction reputation and trust while particular attention is paid to the effect of suburbanization on existing associational networks the social cohesiveness of business culture and the cultural identity of the merchant community as a whole. | Networks of Influence and Power Business Culture and Identity in Liverpool's Merchant Community c. 1800 to 1914

GBP 205.00
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Role of Dams and Reservoirs in a Successful Energy Transition Proceedings of the 12th ICOLD European Club Symposium 2023 (ECS 2023 Interlak

Role of Dams and Reservoirs in a Successful Energy Transition Proceedings of the 12th ICOLD European Club Symposium 2023 (ECS 2023 Interlak

Today new and unexpected challenges arise for Europe’s large array of existing dams and fresh perspectives on the development of new projects for supporting Europe’s energy transition have emerged. In this context the 12th ICOLD European Club Symposium has been held in September 2023 in Interlaken Switzerland. The overarching Symposium theme was on the Role of dams and reservoirs in a successful energy transition. The articles collected in this report book (consisting of a 250-page abstract book and a 1010-page full paper USB) cover the various themes developed during the symposium: - Dams and reservoirs for hydropower - Dams and reservoirs for climate change adaptation - Impact mitigation of dams and reservoirs - How to deal with ageing dams In conjunction with the Symposium the 75th anniversary of the Swiss Committee on Dams offered an excellent opportunity to not only draw from the retrospective of Switzerland’s extensive history of dam development but to also reveal perspectives on the new role of dams for a reliable and affordable energy transition. These aspects are illustrated by several articles covering the various activities challenges and concerns of the dam community. | Role of Dams and Reservoirs in a Successful Energy Transition Proceedings of the 12th ICOLD European Club Symposium 2023 (ECS 2023 Interlak

GBP 230.00
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Effects Conservation Tillage On Ground Water Quality Nitrates and Pesticides

Effects Conservation Tillage On Ground Water Quality Nitrates and Pesticides

Nowadays the environmental sustainability of the cropping systems is increasingly requested by the consumers. Conventional tillage practices totally turning over the soil between the vineyard rows may cause erosion due to rain as well as structure destruction of the soil in the long term. Conservation tillage is a soil management technique poorly widespread in Sardinia allowing cover cropping between vineyard rows. Furthermore this technique makes the canopy development control of herbage possible by cutting it up during specific phenological phases. Conservation tillage usually involves direct benefits to farmers such as increasing soil fertility as well as reductionof tillage costs soil erosion and carbon dioxide (CO2) emissions in the atmosphere. This long term trial during at least five years aims to assess the conservation tillage impact on chemical-physical soil characteristics in comparison with traditional tillage by evaluating the change of organic matter C. E. C. and availability of major plant nutrients in the soil and to estimate their probable rise. The field plots are located in a 35% slope condition vineyard showing massive erosion problem and organic matter low content. A split/plot design with four replications was set up with the comparison between conservation and traditional tillage apart as main plots. Moreover the effects of two different irrigation levels were evaluated in the subplots of each main plot. At the beginning of the trial (2011) a pedological survey was made. Three soil profiles were described and sampled along the field slope and soil sampling in each plot were made both to characterize the soil and to find the zero point. The soil chemical and physical characteristics were monitored through a second soil sampling made at the end of 2013. Conservation tillage caused increasing organic matter content and C. E. C. values. As for major plant nutrients in soil results were more uncertain. Grapevine yield and quality parameters did not show any negative effect when passing from conventional to conservation tillage techniques. The trial provided a preliminary positive evaluation of conservation tillage. However more years are required to confirm this trend. | Effects Conservation Tillage On Ground Water Quality Nitrates and Pesticides

GBP 180.00
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The New S Language

The New S Language

This book provides documentation for a new version of the S system released in 1988. The new S enhances the features that have made S popular: interactive computing flexible graphics data management and a large collection of functions. The new S features make possible new applications and higher-level programming including a single unified language user defined functions as first-class objects symbolic computations more accurate numerical calculations and a new approach to graphics. S now provides direct interfaces to the poowerful tool of the UNIX operating system and to algorithms implemented in Fortran and C. | The New S Language

GBP 325.00
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Hair and Scalp Disorders Medical Surgical and Cosmetic Treatments Second Edition

Hair and Scalp Disorders Medical Surgical and Cosmetic Treatments Second Edition

A succinct and comprehensive guide examining the treatment of hair and scalp disorders with a special emphasis on how hair type morphology and ethnicity can impact on hair disease and treatment. This updated and revised second edition builds on a successful first edition with additional chapters on dermoscopy on how technology can best be integrated into clinical practice and on aging hair. | Hair and Scalp Disorders Medical Surgical and Cosmetic Treatments Second Edition

GBP 180.00
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Diradicaloids

Diradicaloids

π-Conjugated molecules with an even number of π-electrons usually have a closed-shell ground state. However recent studies have demonstrated that a certain type of molecules could show open-shell singlet ground state and display diradical-like (diradicaloid) behavior. Their electronic structure can be understood in terms of the “diradical character” and “aromaticity” concepts. They display very different electronic properties from traditional closed-shell π-conjugated molecules and could be used as next-generation molecular materials. This book provides a comprehensive review on the chemistry physics and material applications of open-shell singlet diradicaloids. Particularly it elaborates the fundamental structure–diradical character–electronic property relationships both theoretically and experimentally. The book has been written by leading scientists in the field from Japan Germany Spain Italy China and Singapore.

GBP 193.00
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The Routledge Handbook of Women and Early Modern European Philosophy

The Routledge Handbook of Women and Early Modern European Philosophy

The Routledge Handbook of Women and Early Modern European Philosophy is an outstanding reference source for the wide range of philosophical contributions made by women writing in Europe from about 1560 to 1780. It shows the range of genres and methods used by women writing in these centuries in Europe thus encouraging an expanded understanding of our historical canon. Comprising 46 chapters by a team of contributors from all over the globe including early career researchers the Handbook is divided into the following sections: I. Context II. Themes A. Metaphysics and Epistemology B. Natural Philosophy C. Moral Philosophy D. Social-Political PhilosophyIII. FiguresIV. State of the Field The volume is essential reading for students and researchers in philosophy who are interested in expanding their understanding of the richness of our philosophical past including in order to offer expanded more inclusive syllabi for their students. It is also a valuable resource for those in related fields like gender and women’s studies; history; literature; sociology; history and philosophy of science; and political science.

GBP 205.00
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Routledge Handbook of Urban Public Space Use Design and Management

Routledge Handbook of Urban Public Space Use Design and Management

Is it truly the end of public space? This handbook presents evidence that the answer is no. In cities in different parts of the world people still use public space to pursue activities of their choice. The book is divided into seven sections. The first section presents three emerging types of public space. Each of the subsequent five sections focuses on a type of activity: recreation commerce protest living and celebration. These sections are international in scope presenting cases of activities in Brazil China Colombia DR Congo Egypt Finland Germany Libya Taiwan Turkey and the U. S. The closing section composed of three chapters presents research methods for studying public space. Graduate students faculty members and researchers in social science architecture landscape architecture geography and urban design will find the book useful for understanding studying and designing urban public space. | Routledge Handbook of Urban Public Space Use Design and Management

GBP 190.00
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A Handbook of Statistical Analyses using SAS

A Handbook of Statistical Analyses using SAS

Updated to reflect SAS 9. 2 A Handbook of Statistical Analyses using SAS Third Edition continues to provide a straightforward description of how to conduct various statistical analyses using SAS. Each chapter shows how to use SAS for a particular type of analysis. The authors cover inference analysis of variance regression generalized linear models longitudinal data survival analysis principal components analysis factor analysis cluster analysis discriminant function analysis and correspondence analysis. They demonstrate the analyses through real-world examples including methadone maintenance treatment the relation of cirrhosis deaths to alcohol consumption a sociological study of children heart transplant treatment and crime rate determinants. With the data sets and SAS code available online this book remains the go-to resource for learning how to use SAS for many kinds of statistical analysis. It serves as a stepping stone to the wider resources available to SAS users.

GBP 180.00
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Vitamins and Minerals in the Prevention and Treatment of Cancer

Vitamins and Minerals in the Prevention and Treatment of Cancer

This book provides researchers and practitioners with a unique collection of current research on the role of vitamins and micronutrients in cancer prevention and treatment. New theories are discussed including a hypothesis that dietary factors may protect against genetically predisposed cancers. Mechanisms by which different vitamins and minerals appear to inhibit carcinogenesis or cell transformation are described including vitamins A C E and selenium protection against oxidative stress by induction of enzymes as catalase and dismutase or inteference with free radical mechanisms; organosulfur compound inhibition of P450 activation enzymes or enhancement of detoxification enzymes; metal ion effects in the modulation of gene expression by site-specific binding of Zn-finger loop domains; B-carotene metabolite up-regulation of gap junctional communication between cells; and vitamin D3 elimination of amplified oncogenes or drug resistant genes. The book also reviews literature implicating a possible relationship between potassium and the control of cancer. Other information presented includes a discussion of contemporary technologies and data associating lipotrope deficiencies with alterations in xenobiotic metabolism nucleic acid methylation purine and pyrimidine synthesis signal transduction and chromosome anomalies. | Vitamins and Minerals in the Prevention and Treatment of Cancer

GBP 205.00
1

Resale Price Maintenance and the Law The Future of Vertical Restraints

Resale Price Maintenance and the Law The Future of Vertical Restraints

The question of how to properly enforce against RPM has been a contentious debate for decades on both sides of the Atlantic. The catalyst is the acceptance that RPM can generate both anti-competitive effects and pro-competitive efficiencies that need to be properly balanced to ensure against Type I/Type II errors and to create viable legislation. Part I focuses on 100 years of US origins and the current legal approach to VR enforcement which reveals the precedent responsible for the transition between per se illegality and the rule of reason thresholds at the federal level. Nine anti-competitive and 19 pro-competitive theoretical models are also introduced to clearly demonstrate the true nonconsensus existent between economists as to whether RPM is deleterious enough to justify a stringent approach to RPM regulation. Part II closely examines the EU origins and current legal structure where RPM has maintained its hardcore by-object designation pursuant to Art. 101(1) TFEU with the consequence of having no safe harbours no applicability of the De Minimus Doctrine an onerous negative rebuttable presumption non-severability of the agreement and almost no chance of obtaining an exemption under Art. 101(3). This is exacerbated by the EC’s lack of guidance on how to prove all conditions necessary for an Art. 101(3) exemption and when a vertical arrangement actually escapes Art. 101(1) applicability. The aim of this book is to examine the economic models historical origins and legal structures of the US/EU regimes to develop proposals on how to modify the EU’s current legal structure to ensure proper enforcement of RPM behaviour that actually enhances legal certainty through a more aligned approach at the national level. Part III proposes five solutions which scrutinise the concepts of appreciability hardcore and by-object restraints to implement modifications to EU’s current legal framework to ensure RPM receives reasonable and equitable treatment in line with economic theory. | Resale Price Maintenance and the Law The Future of Vertical Restraints

GBP 180.00
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Charterparties Law Practice and Emerging Legal Issues

Charterparties Law Practice and Emerging Legal Issues

This book consists of edited versions of the papers delivered at the Institute of International Shipping and Trade Law’s 12th International Colloquium at Swansea Law School in September 2016. Featuring a team of contributors at the top of their profession both in practice and academia these papers have been carefully co-ordinated so as to ensure to give the reader a first class insight into the issues surrounding charterparties. The book is set out in three parts. Part I offers a detailed and critical analysis of issues of contemporary importance concerning time charters. Part 2 carries out a similar analysis with regard to voyage charterparties. Part 3 deliberates issues common to both type of charterparties. Offering critical analysis of contemporary legal issues on charterparty contracts this book considers recent legal and practical developments and is therefore essential reading for both professional and academic readers with an interest in charterparties. | Charterparties Law Practice and Emerging Legal Issues

GBP 270.00
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Learn to Code with Games

Learn to Code with Games

A novel approach for the classroom or self-study Learn to Code with Games makes coding accessible to a broad audience. Structured as a series of challenges that help you learn to code by creating a video game each chapter expands and builds your knowledge while providing guidelines and hints to solving each challenge. The book employs a unique problem-solving approach to teach you the technical foundations of coding including data types variables functions and arrays. You will also use techniques such as pseudocode and process mapping to formulate solutions without needing to type anything into a computer and then convert the solutions into executable code. Avoiding jargon as much as possible Learn to Code with Games shows you how to see coding as a way of thinking and problem solving rather than a domain of obscure languages and syntaxes. Its practical hands-on approach through the context of game development enables you to easily grasp basic programming concepts.

GBP 180.00
1

Marvelous Modular Origami

Marvelous Modular Origami

This richly illustrated book provides step-by-step instructions for the construction of over 30 different modular origami structures. The author describes basic folding techniques required to construct themodules that are used as building blocks to construct complex ornamental models. The diagrams are clear crisp and easy to follow and are accompanied by inspiring color photographs. Additional tips encourage the reader to design their own original creations. Advance Praise for Marvelous Modular Origami A must-have for any modular origami polyhedra enthusiast. Rona Gurkewitz co-author of Multimodular Origami Polyhedra The models are paper folding in its purest form. They range from simple Sonobe to floral and geometrical constructions. All are eye-catching and satisfying to fold and the finished constructions are pleasing to behold. Also included are short sections on the mathematics behind the shapes and optimum color choices. David Petty author of Origami A-B-C In this colorful book you'll find wonderful original origami modular creations. Meenakshi's clear instructions and helpful hints will have you zipping through these modules as well as improvising your own. Rachel Katz co-author of FUN FOLDS: Language Learning Through Paper Folding Marvelous Modular Origami is a colorful addition to the literature of mathematical origami. Florence Temko author of many origami and other craft books

GBP 180.00
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Computational Modelling of Concrete Structures Proceedings of the Conference on Computational Modelling of Concrete and Concrete Structures

Computational Modelling of Concrete Structures Proceedings of the Conference on Computational Modelling of Concrete and Concrete Structures

The EURO-C conference series (Split 1984 Zell am See 1990 Innsbruck 1994 Badgastein 1998 St. Johann im Pongau 2003 Mayrhofen 2006 Schladming 2010 St. Anton am Arlberg 2014 and Bad Hofgastein 2018) brings together researchers and practising engineers concerned with theoretical algorithmic and validation aspects associated with computational simulations of concrete and concrete structures. Computational Modelling of Concrete Structures reviews and discusses research advancements and the applicability and robustness of methods and models for reliable analysis of complex concrete reinforced concrete and pre-stressed concrete structures in engineering practice. The contributions cover both computational mechanics and computational modelling aspects of the analysis and design of concrete and concrete structures: Multi-scale cement and concrete research: experiments and modelling Aging concrete: from very early ages to decades-long durability Advances in material modelling of plain concrete Analysis of reinforced concrete structures Steel-concrete interaction fibre-reinforced concrete and masonry Dynamic behaviour: from seismic retrofit to impact simulation Computational Modelling of Concrete Structures is of special interest to academics and researchers in computational concrete mechanics as well as industry experts in complex nonlinear simulations of concrete structures. | Computational Modelling of Concrete Structures Proceedings of the Conference on Computational Modelling of Concrete and Concrete Structures

GBP 290.00
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Drug Delivery with Targeted Nanoparticles In Vitro and In Vivo Evaluation Methods

Drug Delivery with Targeted Nanoparticles In Vitro and In Vivo Evaluation Methods

Nanotechnology has the potential to change every part of our lives. Today nanotechnology-based products are used in many areas and one of the most important areas is drug delivery. Nanoparticulate drug delivery systems not only provide controlled delivery of drugs and improved drug solubility but also improve drug efficiency and reduce side effects via targeting mechanisms. However compared with conventional drug delivery systems few nanoparticle-based products are on the market and almost all are nontargeted or only passively targeted systems. In addition obtaining targeted nanoparticle systems is quite complex and requires several evaluation mechanisms. This book discusses the production characterization regulation and currently marketed targeted nanoparticle systems in a broad framework. It provides an overview of targeted nanoparticles’ (i) in vitro characterization such as particle size stability ligand density and type; (ii) in vivo behavior for different targeting areas such as tumor brain and vagina; and (iii) current advances in this field including clinical trials and regulation processes. | Drug Delivery with Targeted Nanoparticles In Vitro and In Vivo Evaluation Methods

GBP 385.00
1

Explosives and Chemical Weapons Identification

Explosives and Chemical Weapons Identification

Chemicalsare a part of daily life and can be found all around us. Many common chemicals when mixed improperly � whether intentionally or not � can pose serious consequences to those who come in contact with them. Written by an author who is an experiencedhazmat-qualifiedfirst responder forensicspecialist and educator Explosives and Chemical Weapons Identification provides the means to quickly identify the type of explosive or chemical weapon at hand upon arriving at the scene. A thorough and accessible reference this book contains the identification capabilities for 468 different formulations for explosives and chemical weapons. It presents detailed descriptions for each of these formulations by breaking down their materials into five concise categories: common name synonym class ingredients and use. The materials are also indexed by common name class and ingredient. A handy reference packed with critical information and over 350 illustrations and photographs to aid in visual identification Explosives and Chemical Weapons Identification is an essential resource that every first responder and forensic professional must have within reach every time.

GBP 200.00
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Electric Machines Two Volume Set

Electric Machines Two Volume Set

With its comprehensive coverage of the state of the art this second edition of the book introduces the basic types of transformers and electric machines and also discusses advanced subjects in electric machines starting from principles to applications and case studies with ample graphical results. The first volume Electric Machines: Steady State Performance with MATLAB® covers circuit modeling characteristics and performance characteristics under steady state testing techniques and preliminary electromagnetic-thermic dimensioning. This book is intended for first semester course treating electric transformers rotary and linear machines steady state modeling and performance computation preliminary dimensioning and testing standardized and innovative techniques. The second volume Electric Machines: Transients Control Principles Finite Element Analysis and Optimal Design with MATLAB® is intended for second (and third) semester course treating topics such as modeling of transients control principles electromagnetic and thermal finite element Analysis and optimal design (dimensioning). Notable recent knowledge with strong industrialization potential has been added to this edition such as orthogonal models of multiphase A. C. machines thermal finite element analysis of (FEA) electric machines and FEA– based–only optimal design of a PM motor case study. Both the volumes include numerical examples and case studies and numerous computer simulation programs in MATLAB and Simulink® are also available online that illustrate performance characteristics present in the chapters. | Electric Machines Two Volume Set

GBP 200.00
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Creating a Lean Culture Tools to Sustain Lean Conversions Third Edition

Creating a Lean Culture Tools to Sustain Lean Conversions Third Edition

Winner of a Shingo Research and Professional Publication Award The new edition of this Shingo Prize-winning bestseller provides critical insights and approaches to make any Lean transformation an ongoing success. It shows you how to implement a sustainable successful transformation by developing a culture that has your stakeholders throughout the organizational chart involved and invested in the outcome. It teaches you how to successfully navigate the politics in cross-functional process improvement projects and to engage executives in ways that are personally meaningful to them. If you are a leader at any level in an organization undergoing or considering a Lean transformation this is where you should start and finish � and start again. Read the Reviews:This book became an instant classic in the literature of professional operations. In this third edition David Mann updates and expands his teaching with five additional years of valuable experience and expertise derived from his very active multi-industry consultancy. I have benefitted greatly from his writing and wholeheartedly recommend this book to be top-of-the desk of any serious Lean practitioner or performance transformation leader. � Raymond C. Floyd two-time Shingo Prize Winner President and CEO Plasco Energy GroupDavid Mann builds substantially on his seminal work on the Lean management system. The book is full of new insight and polishes the most important ideas about Lean management. The new chapter on engaging executive leadership alone is worth the price of the book. � Peter Ward Richard M. Ross Professor and Chair Department of Management Science Fisher College of Business The Ohio State UniversityThis book has long been my �go-to� guide on Lean management practices that help create a culture of continuous improvement and excellence. I have recommended the book to countless healthcare leaders who rave about how he | Creating a Lean Culture Tools to Sustain Lean Conversions Third Edition

GBP 180.00
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Sport Pedagogy An Introduction for Teaching and Coaching

Sport Pedagogy An Introduction for Teaching and Coaching

Sport Pedagogy offers an essential starting point for anyone who cares about sport education and young people. It offers invaluable theoretical and practical guidance for studying to become an effective teacher or coach and for anyone who wants to inspire children and young people to engage in and enjoy sport for life. The book also focuses on you as a learner in sport prompting you to reflect critically on the ways in which your early learning experiences might affect your ability to diagnose the learning needs of young people with very different needs. Sport Pedagogy is about learning in practice. It refers both the ways in which children and young people learn and the pedagogical knowledge and skills that teachers and coaches need to support them to learn effectively. Sport pedagogy is the study of the place where sport and education come together. The study of sport pedagogy has three complex dimensions that interact to form each pedagogical encounter: Knowledge in context - what is regarded as essential or valuable knowledge to be taught coached or learnt is contingent upon historical social and political contextual factors that define practice; Learners and learning -at the core of sport pedagogy is expertise in complex learning theories and a deep understanding of diversity and its many impacts on the ways in which young learners can learn; Teachers/teaching and coaches/coaching - effective teachers and coaches are lifelong learners who can harness the power of sport for diverse children and young people. Gaining knowledge and understanding of the three dimensional concept of sport pedagogy is the first step towards ensuring that the rights of large numbers of children and young people to effective learning experiences in and through sport are not denied. The book is organised into three sections: background and c | Sport Pedagogy An Introduction for Teaching and Coaching

GBP 180.00
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Hematopoietic Stem Cell Transplantation and Cellular Therapies for Autoimmune Diseases

Hematopoietic Stem Cell Transplantation and Cellular Therapies for Autoimmune Diseases

This book summarizes the global progress in medical and scientific research toward converting traditionally chronic autoimmune diseases into a drug-free reversible illness using hematopoietic stem cell transplantation (HSCT) and other cellular therapies such as T regulatory cells (Treg) mesenchymal stromal/stem cells and chimeric antigen receptor T (CAR T) cells in order to reintroduce sustained immune tolerance. This title provides information on different types of stem cells and immune cells; post-transplant immune regeneration; cellular regulatory requirements; ethical and economic considerations; and the advantages and disadvantages of HSCT in the treatment of a variety of autoimmune diseases versus current conventional treatments. Arranged by disease the text provides a comprehensive guide to HSCT for all types of autoimmune/immune disorders including monogenetic autoimmune diseases; autoimmune aplastic anemia; neurologic immune diseases including multiple sclerosis chronic inflammatory demyelinating polyneuropathy neuromyelitis optica and stiff person syndrome; rheumatologic diseases such as systemic sclerosis and systemic lupus erythematosus; dermatologic diseases such as pemphigus; gastrointestinal disorders such as Crohn’s disease and celiac disease; and immune-mediated endocrinologic disease type I diabetes mellitus. Guidance is provided on the transplantation technique cell collection and processing conditioning regimens infections and early and late complications. Key Features Outlines therapies and techniques for HSCT for autoimmune diseases Discusses the advantages of HSCT over conventional therapies Reviews the entire process of stem cell therapy from harvest and ethics to indications efficacy and regulatory oversight | Hematopoietic Stem Cell Transplantation and Cellular Therapies for Autoimmune Diseases

GBP 180.00
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